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Detailed Program
Paper Number : BI-I01
Time Frame : 13:30~13:55
Presentation Date : Thurse day, 27, November
Session Name : Biomaterials
Session Chair 1# : Byong Taek Lee
Session Chair 2# : Il Young Kim
GRAPE¢ç technology: in vitro and in vivo evaluations
K. Uetsuki
Nakashima Medical Co.
Dry titanium oxide layer is the last to deposit apatite in vitro, though titanium alloys with such layer have known to be compatible to bone tissue as they form relatively firm bonds with living bone tissue. Applying a narrow and confined space to titanium substrates with dry titania layer derived by heating in air at ~500¡ÆC enhanced the ability of apatite deposition under in vitro and in vivo environments. We denoted this as GRAPE¢ç technology after GRoove and ApatitE. The narrow space was derived by groove machining or pits, or by set a pair of titanium substrates with <1mm distance. In vitro apatite deposition will be presented for such specimens in Kokubo solution (SBF) as well as new bone tissue generation. From a series of experiments where the titanium substrates with dry titania layer were exposed to still and flowing SBF, the mechanism will be proposed to explain such apatite depositing behavior.
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