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Detailed Program
Paper Number : NA-I03
Time Frame : 13:30~13:55
Presentation Date : Friday, 28, November
Session Name : Nano-particles & Nano-structured Materials
Session Chair 1# : Hae Jin Hwang
Session Chair 2# : Tohru Sekino
Synthesis of Magnetite Nanoparticles and Their Surface Modification For Hyperthermia Application
Chang-Yeoul Kim
Korea Institute of Ceramic Engineering and Technology
Keywords: magnetite, nanocrystals, hyperthermia, surface modification

Magnetite nanocrystals draw many attractions of their applications for hyperthermia therapy; cancer killing by heating. These days, hyperthermia together with chemotherapy shows improved cancer treatment effects. So, we successfully synthesized magnetite nanoparticles by thermal decomposition method or coprecipitaton method. We try to synthesize magnetite nanoparticles and evaluate the hyperthermia effect by measuring temperature rise under ac inductive magnetic field. We also suggest the method of magnetic nanoparticle’s dispersion within phosphor buffer solution and aerogel or silicone matrices. We could present the possibilities of the dispersion of magnetite nanoparticles with molar concentration change by surface modification using PEG within PBS and showed hyperthermia effects; the temperature increased when 689 Oe of magnetic field was applied. PEG coating give two merits: the homogeneous dispersion of the NPs and the hyperthermia effects of the NPs under alternating magnetic field, and the drug delivery because of bio-compatibility.

References:

[1] Eun-Hee Lee, Chang-Yeoul Kim, Yong-Ho Choa, Current Applied Physics 12, 2012, P47–52,
[2] CY Kim, L Xu, EH Lee, Journal of the Korean Physical Society 65,2 (2014,), pp 261-266
[3] CY Kim, L Xu, EH Lee, YH Choa, Advances in Polymer Technology, Volume 32, Issue S1, 714–E723, 2013
Acknowledgements :